Extracellular Vesicle Diagnostic Testing Kit

Tissue specific signatures could improve future diagnostics

  • Simple blood test
  • Biomarkers of brain, heart, kidney, lung and liver
  • May yield early strategies for early diagnosis

 
Licensing Manager: AJ Crawford
ayrianne.crawford@unmc.edu or 402-559-4098
 

Description

Tissue specific signatures could improve future diagnostics

UNMC researchers have identified a blood-based approach for detecting tissue-specific exosomes.
 
Exosomes are cellular excretions that are useful as biomarkers and diagnostics because they contain diverse tissue specific cargo, including any products of the cell like fats, proteins, DNAs and RNAs. UNMC researchers have identified tissue specific markers on exosomes that help identify their origin. Exosome markers for brain, heart, kidney, lung, and liver tissues have been identified. These unique signatures help identify tissue-specific biomarkers, and potentially aid in the development of new diagnostics.
 
Signatures have been validated in animal and human cadaver specimens, and will enable future diagnostic tests.
 
To discuss licensing opportunities please contact AJ Crawford, at ayrianne.crawford@unmc.edu or 402-559-4098.
 

Additional Info

Publications

  • Comprehensive Characterization of Nanosized Extracellular Vesicles from Central and Peripheral Organs: Implications for Preclinical and Clinical Applications, ACS Applied Nano Materials